ebooks and download videos Search All  Title  Author 
Home / Nonfiction / Medical / Toxicology

Presystemic Drug Elimination: Butterworths International Medical Reviews: Clinical Pharmacology and Therapeutics

| £60.78 | €68.36 | Ca$98.61 | Au$97.32
by Charles F. George
What is this?DRM-PDF | by download   add to wish list
Presystemic Drug Elimination: Butterworths International Medical Reviews: Clinical Pharmacology and Therapeutics by Charles F. George

Butterworths International Medical Reviews, Clinical Pharmacology and Therapeutics 1: Presystemic Drug Elimination explores the principles of presystemic drug metabolism in human based on animal studies. This book is divided into four sections encompassing 10 chapters that specifically describe the extent of metabolism occurring in the gastrointestinal tract, liver, and lung.
Section 1 focuses on presystemic elimination by the gastrointestinal tract. This section discusses the enzymatic biotransformation in the gastrointestinal mucosa and the ability of the microflora to metabolize drugs. Section 2 considers the contribution of the liver to presystemic drug elimination, with a particular emphasis on the physiological factors, which determine the rate of breakdown of drugs in vivo. This section also deals with the effects of hepatic cirrhosis on presystemic drug elimination. Section 3 presents first a brief outline of the knowledge of pulmonary structure and relevant physiology, followed by a discussion on "first-passÂ" metabolism of endogenous substrates and drugs across the pulmonary circulation and of environmental chemicals after inhalation. This section also provides the methods for distinguishing between the contribution of the various sites to presystemic drug elimination and the problems associated with attempts to analyze available pharmacokinetic data.
This work is an ideal source for clinical pharmacologists and researchers

To view this DRM protected ebook on your desktop or laptop you will need to have Adobe Digital Editions installed. It is a free software. We also strongly recommend that you sign up for an AdobeID at the Adobe website. For more details please see FAQ 1&2. To view this ebook on an iPhone, iPad or Android mobile device you will need the Adobe Digital Editions app, or BlueFire Reader or Txtr app. These are free, too. For more details see this article.

SHARE  Share by Email  Share on Facebook  Share on Twitter  Share on Linked In  Share on Delicious
or call in the US toll free 1-888-866-9150 product ID: 618909

Ebook Details
Pages: 224
Size: 27.1 MB
Publisher: Butterworth-Heinemann
Date published:   1982
ISBN: 9781483163604 (DRM-PDF)

DRM Settings
Read Aloud:  not allowed

This product is listed in the following category:

Nonfiction > Medical > Toxicology

If you find anything wrong with this product listing, perhaps the description is wrong, the author is incorrect, or it is listed in the wrong category, then please contact us. We will promptly address your feedback.

Submit 5 page SummaryWhat is this?

© 2016